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Cosmetics, Pharmaceuticals and Food

The ingredients of many drugs are sensitive to heat and quickly lose their effect due to heat influence. This is the case, for example, with emulsions, which often change their consistency even at summary temperatures while separating into constituents.In addition, fats contained in the emulsion can spoil, making the drug unusable.

Many medicines need to be kept refrigerated so as not to decompose as quickly. In Germany, there are more than 2,000 refrigerated or cold chain products such as special vaccines, asthma sprays, and insulins which may only exceed a temperature of 8 ° C for a short time. In addition to the chemistry for doctors, there are also numerous cosmetic products such as lotions which are sensitive to heat and therefore require special protection.

It is possible to reduce the reaction of drugs to thermal influences with suitable packaging. However, to find the right packaging, it is necessary to know the characteristics of the ingredients used.

Investigation methods such as thermal analysis and calorimetry are used in the field of pharmacology primarily to characterize the main active ingredients and to determine the pharmaceutical dosage form. Due to their high sensitivity, the instruments from LINSEIS enable the smallest thermal reactions to be detected with extremely small amounts of sample. This makes them ideal for use in this sensitive area.

Chip-DSC 10

Chip-DSC-10
  • The perfect DSC for Quality control and Education
  • Cost effective, space saving and highly innivative Chip DSC
  • -180 up to 600°C (LN2 Quench cooling)
Details

Chip-DSC 100

Chip-DSC-100
  • Unique Chip Technology – The next step in DSC
  • Modular expandable design (Sample Robot, Cooling options etc.)
  • Temperature range -180 up to 600°C (Peltier cooling, Closed-loop Intracooler or LN2 cooling)
Details

STA PT 1000

STA-PT1000
  • (TGA) Thermogravimety and (DSC) Differential Scanning Calorimetry
  • True top loading TG-DSC heat flux sensors
  • Numerous user excheangable TG, TG-DSC and TG-DTA sensors for any kind of application
  • Modular design: sample robot, turntable for up to two furnaces, vacuum tight design, different gas dosing systems, high pressure (up to 5 bar) option, vapor dosing system etc.
  • Temperature range: -150 up to 1600/1750/2000/2400°C
Details

TGA PT 1000

TGA-1000
  • Toploading low drift Thermobalance (TGA) 
  • High speed microfurnace for very fast heating and cooling
  • Many acessories such as: gas dosing systems, sample robot, MS/FTIR coupling etc.
  • Temperature range RT up to 1100°C
Details

TMA PT 1000

TMA-1000
  • High performace Thermomechanical Analysis (TMA)
  • highest resolution LVDT displacement sensor with a digital resolution of 0.125nm/digit
  • Adjustable force and frequency
  • Temperature range: -150 up to 1000°C or special version -260 up to +220°C
Details

EGA FTIR

EGA Pfeiffer

The combination of a Linseis Thermal Analyzer with a FTIR is especially interesting in fields such as polymers, chemical and pharmaceutical industry. Linseis has more than 20 years experience in providing a integrated hard- and software concept. For interpretation different libraries are available.

Details

EGA GCMS

EGA Pfeiffer

The QMS – quadrupole mass spectrometer coupling device is a state of the art mass spectrometer with a heated inlet system. The QMS is used for the analysis of volatile decompositions. All Linseis instruments are especially designed to guarantee a user friendly operation of both the Thermal Analyzer and the Mass Spectrometer. A integrated Software solution is certainly available.

Details

EGA In-Situ

EGA Pfeiffer

By coupling a Termobalance (TGA) or a Simultaneous Thermal Analyzer (STA) with a (GC-MS) Gas chromatography–mass spectrometry which is an analytical method that combines the features of gas-chromatography and mass spectrometry, one can combine the strength on these two tools. Applications of GC-MS include drug detection, environmental analysis, explosives, and identification of unknown samples.

Details

EGA QMS

EGA Pfeiffer

An optical In-Situ Analysis offers many advantages such as: no Cooling / Modification of the measuring gas (for example no out-condensation, no transition reaction and no equilibrium shift).
Many materials with high condensation temperature for example alkali metals (Na, K and their combinations) are now able to be measured, heated capillary only suitable for some 200 – 250°C, the optical port allows measurement until 1600°C

Details