Material Analysis for the Pharmaceutical, Food, and Life Sciences Industries
Precise thermal characterization of active ingredients, foods, proteins, and biological materials
Active pharmaceutical ingredients, food products, proteins, and biological materials are often particularly sensitive to temperature, humidity, and storage conditions. Even slight temperature fluctuations can have a significant impact on their stability, efficacy, consistency, shelf life, or biological function.
Modern thermal analysis methods enable the precise investigation of melting and glass transitions, denaturation processes, moisture loss, decomposition reactions, and polymorphic structures. This makes it possible to optimize formulations, determine suitable storage conditions, and ensure consistent product quality.
With over 69 years of experience, LINSEIS offers high-performance measurement systems for sensitive samples and very small sample volumes. The systems support research, development, and quality control in the pharmaceutical industry, food technology, biotechnology, and the life sciences.
Typical Applications in the Pharmaceutical, Food, and Life Sciences Industries
Select your specific application to gain detailed insights into measurement methods and solutions for pharmaceutical, biological, and food technology challenges.
Thermal Stability of Active Ingredients
Analysis of melting behavior, polymorphism, decomposition, and thermal stability of active pharmaceutical ingredients and formulations.
Aging & Shelf Life
Investigation of storage stability, moisture content, oxidation, and temperature-related changes in pharmaceuticals, food products, and cosmetics.
Protein Analysis
Characterization of protein folding, denaturation, aggregation, and molecular interactions for biotechnology and pharmaceutical development.
Measurement Methods for the Pharmaceutical, Food, and Life Sciences Industries
Differential Scanning Calorimetry (DSC)
Determination of melting behavior, glass transitions, crystallization, polymorphism, and thermal stability.
Thermogravimetry (TGA)
Analysis of moisture, loss on drying, volatile components, and thermal decomposition.
Simultaneous Thermal Analysis (STA)
Simultaneous analysis of mass changes and thermal effects for comprehensive material characterization.
Gravimetric Sorption Analysis (GSA)
Determination of moisture absorption, sorption and desorption behavior, and interactions with water vapor and gases.
Microcalorimetry (CAL)
Highly sensitive measurement of minute thermal effects in biological, pharmaceutical, and chemical processes.
Thermomechanical Analysis (TMA)
Determination of dimensional changes and thermomechanical properties of packaging materials, biomaterials, and pharmaceutical excipients.
Recommended Equipment for the Pharmaceutical, Food, and Life Sciences Industries
Top Devices
CAL L92 - Micro-
calorimeter
UDSC L64 - Ultimate DSC
DSC L63
Other Devices
Selected Real-World Measurement Examples
Real-world measurements demonstrate how thermal analysis methods are used for development, stability assessment, and quality assurance in the pharmaceutical, food, and life sciences industries.
Thermal Analysis of Historic Violin Wood
Thermal Characterization of Desloratadine Polymorphs
DSC measurements with the LINSEIS DSC L63 show the characteristic melting and phase transition behavior of various desloratadine polymorphs. The measurement results enable unambiguous identification of the individual crystal forms and provide valuable insights for polymorph characterization, formulation development, and pharmaceutical quality control. Download the white paper to learn more about the complete measurement setup, DSC analysis, and the interpretation of the measurement results.
