{"id":44140,"date":"2024-07-12T21:48:10","date_gmt":"2024-07-12T19:48:10","guid":{"rendered":"https:\/\/www.linseis.com\/?post_type=applikationen&#038;p=44140"},"modified":"2024-10-18T15:46:05","modified_gmt":"2024-10-18T13:46:05","slug":"chip-dsc-10-dsc-de-produits-pharmaceutiques-point-vitreux-sorbitol","status":"publish","type":"applikationen","link":"https:\/\/www.linseis.com\/fr\/votre-industrie\/cosmetiques-produits-pharmaceutiques-et-aliments\/chip-dsc-10-dsc-de-produits-pharmaceutiques-point-vitreux-sorbitol\/","title":{"rendered":"Chip-DSC 10 &#8211; DSC de produits pharmaceutiques &#8211; Temp\u00e9rature de transition vitreuse du sorbitol"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"44140\" class=\"elementor elementor-44140 elementor-5966\" data-elementor-post-type=\"applikationen\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0450a0a e-flex e-con-boxed e-con e-parent\" data-id=\"0450a0a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2d4cc42 e-con-full e-flex e-con e-child\" data-id=\"2d4cc42\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6418b89 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"6418b89\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:500}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/www.linseis.com\/startseite\/methoden\/dynamische-differenz-kalorimetrie\/\"><strong>La DSC<\/strong> <\/a>peut \u00eatre un outil d&rsquo;analyse des m\u00e9dicaments en vue du contr\u00f4le qualit\u00e9, de la recherche et du d\u00e9veloppement et de la caract\u00e9risation des produits.<\/p><p>En plus de la composition d&rsquo;un m\u00e9dicament, sa <a href=\"https:\/\/www.linseis.com\/fr\/connaissance\/cristallisation-et-recristallisation-des-polymeres\/\"><strong>structure cristalline<\/strong><\/a> et sa phase sont importantes et d\u00e9crites par des brevets.<br \/>De petites modifications de l&rsquo;humidit\u00e9 et de la composition peuvent affecter la structure et donner un produit diff\u00e9rent avec un mode d&rsquo;action diff\u00e9rent.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-26e9b16 e-flex e-con-boxed e-con e-parent\" data-id=\"26e9b16\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b5265ab elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"b5265ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"493\" src=\"https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-1024x631.png\" class=\"attachment-large size-large wp-image-24847\" alt=\"\" srcset=\"https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-1024x631.png 1024w, https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-300x185.png 300w, https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-768x474.png 768w, https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-1536x947.png 1536w, https:\/\/www.linseis.com\/wp-content\/uploads\/2024\/07\/Chip-DSC-Pharma-2-glass-2048x1263.png 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6aa6f2e e-flex e-con-boxed e-con e-parent\" data-id=\"6aa6f2e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-94cd28e e-con-full e-flex e-con e-child\" data-id=\"94cd28e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-138c71d elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"138c71d\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:500}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Dans cet exemple, le sorbitol, un sucre-alcool synth\u00e9tique C-6 couramment utilis\u00e9 comme substitut du sucre dans les confiseries, les produits di\u00e9t\u00e9tiques et comme excipient pour les m\u00e9dicaments, a \u00e9t\u00e9 analys\u00e9 avec l&rsquo;appareil <a href=\"https:\/\/www.linseis.com\/fr\/produits\/dsc-differential-scanning-calorimetry\/chip-dsc-10\/\"><strong>Chip-DSC 10 <\/strong><\/a>avec un\u00a0 dispositif de refroidissement \u00e0 trempe.<\/p><p>Le but de la mesure \u00e9tait de montrer l&rsquo;influence du degr\u00e9 d&rsquo;humidit\u00e9 sur la structure du produit.<\/p><p>Deux \u00e9chantillons, l&rsquo;un contenant 5,4 % d&rsquo;eau et l&rsquo;autre exempt d&rsquo;eau, ont \u00e9t\u00e9 analys\u00e9s entre -70 \u00b0C et +50 \u00b0C.<br \/>On constate que la <a href=\"https:\/\/www.linseis.com\/fr\/connaissance\/temperature-de-transition-du-verre\/\"><strong>temp\u00e9rature de transition vitreuse<\/strong><\/a> du sorbitol anhydre (courbe bleue) \u00e0 -3,9 \u00b0C chute \u00e0 -28,7 \u00b0C lorsque l&rsquo;\u00e9chantillon contient 5,4 % d&rsquo;eau (courbe rouge).<\/p><p>Cela peut \u00e9galement affecter la structure cristalline du solide et peut \u00eatre important pour les conditions de stockage.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ecd1f0e e-flex e-con-boxed e-con e-parent\" data-id=\"ecd1f0e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2abea73 e-con-full e-flex e-con e-child\" data-id=\"2abea73\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d60d9e2 e-con-full e-flex e-con e-child\" data-id=\"d60d9e2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-612ac73 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"612ac73\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Instrument de mesure appropri\u00e9<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fdc84c2 e-flex e-con-boxed e-con e-parent\" data-id=\"fdc84c2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-67c5679 e-con-full e-flex e-con e-child\" data-id=\"67c5679\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c23a354 elementor-widget elementor-widget-loop-carousel\" data-id=\"c23a354\" data-element_type=\"widget\" data-e-type=\"widget\" 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.elementor-element.elementor-element-fe9af43{--content-width:100%;}}@media(max-width:767px){.elementor-41180 .elementor-element.elementor-element-fe9af43{--padding-top:30px;--padding-bottom:30px;--padding-left:30px;--padding-right:30px;}.elementor-41180 .elementor-element.elementor-element-c049c96 img{max-width:90px;}.elementor-41180 .elementor-element.elementor-element-c049c96 > .elementor-widget-container{margin:0px -10px -60px 0px;}}\/* Start custom CSS for image, class: .elementor-element-c550419 *\/.elementor-41180 .elementor-element.elementor-element-c550419 img:hover {transform:scale(1.2) ;}\n\nimg {transition:0.5s;}\/* End custom CSS *\/\n\/* Start custom CSS for button, class: .elementor-element-157efd1 *\/:hover {transform: 100px}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"41180\" class=\"elementor elementor-41180 elementor-374 elementor-374 swiper-slide e-loop-item e-loop-item-41697 post-41697 messgeraete type-messgeraete status-publish hentry category-analyse-thermique category-dsc-dynamische-differenz-kalorimetrie-dynamique-de-la-difference-de-calorimetrie\" data-elementor-post-type=\"elementor_library\" role=\"group\" aria-roledescription=\"slide\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-fe9af43 e-flex e-con-boxed e-con e-parent\" data-id=\"fe9af43\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c78ad0b e-con-full e-flex e-con e-child\" data-id=\"c78ad0b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c550419 elementor-invisible elementor-widget elementor-widget-image\" data-id=\"c550419\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.linseis.com\/fr\/produits\/dsc-differential-scanning-calorimetry\/chip-dsc-l66-advanced\/\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/www.linseis.com\/wp-content\/uploads\/2025\/07\/Produktbild_Chip-DSC_1200-x-1500-819x1024.png\" class=\"attachment-large size-large wp-image-88177\" alt=\"\" srcset=\"https:\/\/www.linseis.com\/wp-content\/uploads\/2025\/07\/Produktbild_Chip-DSC_1200-x-1500-819x1024.png 819w, https:\/\/www.linseis.com\/wp-content\/uploads\/2025\/07\/Produktbild_Chip-DSC_1200-x-1500-240x300.png 240w, https:\/\/www.linseis.com\/wp-content\/uploads\/2025\/07\/Produktbild_Chip-DSC_1200-x-1500-768x960.png 768w, https:\/\/www.linseis.com\/wp-content\/uploads\/2025\/07\/Produktbild_Chip-DSC_1200-x-1500.png 1200w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c4f48b3 e-con-full e-flex e-con e-child\" data-id=\"c4f48b3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0e7301b elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"0e7301b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:250}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Chip-DSC 10<br> (Chip-DSC<br> L66 Advanced)<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-26c3b66 e-con-full e-flex e-con e-child\" data-id=\"26c3b66\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7c0cf9 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"c7c0cf9\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:500}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tUn concept de capteur r\u00e9volutionnaire\r\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-157efd1 btn-simple elementor-invisible elementor-widget elementor-widget-button\" data-id=\"157efd1\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;_animation_delay&quot;:750}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.linseis.com\/fr\/produits\/dsc-differential-scanning-calorimetry\/chip-dsc-l66-advanced\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" id=\"Ebene_1\" data-name=\"Ebene 1\" viewBox=\"0 0 12 12\"><g id=\"Gruppe_2757\" data-name=\"Gruppe 2757\"><g id=\"Gruppe_2756\" data-name=\"Gruppe 2756\"><path id=\"Pfad_2826\" data-name=\"Pfad 2826\" d=\"M4.051,1.129L.98,10.871h2.523L6.58,1.129h-2.529Z\" fill=\"#0870b8\" stroke-width=\"0\"><\/path><path id=\"Pfad_2827\" data-name=\"Pfad 2827\" d=\"M8.491,1.129l-3.071,9.742h2.523L11.02,1.129h-2.529Z\" fill=\"#0870b8\" stroke-width=\"0\"><\/path><\/g><\/g><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">En savoir 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